Combination of the c-Met Inhibitor Tivantinib and Zoledronic Acid Prevents Tumor Bone Engraftment and Inhibits Progression of Established Bone Metastases in a Breast Xenograft Model

Bone is the most common metastatic site for breast cancer. There is a significant need to understand the molecular mechanisms controlling the engraftment and growth of tumor cells in bone and to discover novel effective therapeutic strategies. The aim of this study was to assess the effects of tivan...

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Detalles Bibliográficos
Autores principales: Previdi, Sara, Scolari, Federica, Chilà, Rosaria, Ricci, Francesca, Abbadessa, Giovanni, Broggini, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832513/
https://www.ncbi.nlm.nih.gov/pubmed/24260160
http://dx.doi.org/10.1371/journal.pone.0079101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832513/
https://www.ncbi.nlm.nih.gov/pubmed/24260160
http://dx.doi.org/10.1371/journal.pone.0079101

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