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Coordination between p21 and DDB2 in the Cellular Response to UV Radiation

The tumor suppressor p53 guides the cellular response to DNA damage mainly by regulating expression of target genes. The cyclin-dependent kinase inhibitor p21, which is induced by p53, can both arrest the cell cycle and inhibit apoptosis. Interestingly, p53-inducible DDB2 (damaged-DNA binding protei...

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Detalles Bibliográficos
Autores principales: Li, Hao, Zhang, Xiao-Peng, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832521/
https://www.ncbi.nlm.nih.gov/pubmed/24260342
http://dx.doi.org/10.1371/journal.pone.0080111