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DDAH1 Deficiency Attenuates Endothelial Cell Cycle Progression and Angiogenesis

Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthase (NOS). ADMA is eliminated largely by the action of dimethylarginine dimethylaminohydrolase1 (DDAH1). Decreased DDAH activity is found in several pathological conditions and is associated with increased risk o...

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Detalles Bibliográficos
Autores principales: Zhang, Ping, Xu, Xin, Hu, Xinli, Wang, Huan, Fassett, John, Huo, Yuqing, Chen, Yingjie, Bache, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832548/
https://www.ncbi.nlm.nih.gov/pubmed/24260221
http://dx.doi.org/10.1371/journal.pone.0079444