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Synthesis of a Pseudo-Disaccharide Library and Its Application to the Characterisation of the Heparanase Catalytic Site

A novel methodology is described for the efficient and divergent synthesis of pseudodisaccharides, molecules comprising of amino carbasugar analogues linked to natural sugars. The methodology is general and enables the introduction of diversity both at the carbasugar and the natural sugar components...

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Detalles Bibliográficos
Autores principales: Vinader, Victoria, Haji-Abdullahi, Mohamed H., Patterson, L. H., Afarinkia, Kamyar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832595/
https://www.ncbi.nlm.nih.gov/pubmed/24260588
http://dx.doi.org/10.1371/journal.pone.0082111