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CD43 Promotes Cells Transformation by Preventing Merlin-Mediated Contact Inhibition of Growth
In normal tissues, strict control of tissue size is achieved by regulating cell numbers. The mechanism that controls total cell number is known as contact inhibition of growth and it depends on the NF2/Merlin pathway. Negative regulation of this pathway by deleterious mutations or by oncogenes resul...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832598/ https://www.ncbi.nlm.nih.gov/pubmed/24260485 http://dx.doi.org/10.1371/journal.pone.0080806 |