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Requirement of PEA3 for Transcriptional Activation of FAK Gene in Tumor Metastasis

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase critically involved in cancer metastasis. We found an elevation of FAK expression in highly metastatic melanoma B16F10 cells compared with its less metastatic partner B16F1 cells. Down-regulation of the FAK expression by either small inte...

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Detalles Bibliográficos
Autores principales: Li, Shufeng, Huang, Xiaofeng, Zhang, Dapeng, Huang, Qilai, Pei, Guoshun, Wang, Lixiang, Jiang, Wenhui, Hu, Qingang, Tan, Renxiang, Hua, Zi-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832605/
https://www.ncbi.nlm.nih.gov/pubmed/24260201
http://dx.doi.org/10.1371/journal.pone.0079336