Crystal Structure of the Pleckstrin Homology Domain from the Ceramide Transfer Protein: Implications for Conformational Change upon Ligand Binding

Ceramide transfer protein (CERT) is responsible for the nonvesicular trafficking of ceramide from the endoplasmic reticulum (ER) to the trans Golgi network where it is converted to sphingomyelin (SM). The N-terminal pleckstrin homology (PH) domain is required for Golgi targeting of CERT by recognizi...

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Detalles Bibliográficos
Autores principales: Prashek, Jennifer, Truong, Trung, Yao, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832616/
https://www.ncbi.nlm.nih.gov/pubmed/24260258
http://dx.doi.org/10.1371/journal.pone.0079590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832616/
https://www.ncbi.nlm.nih.gov/pubmed/24260258
http://dx.doi.org/10.1371/journal.pone.0079590

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