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An Association Study between Hypoxia Inducible Factor-1alpha (HIF-1α) Polymorphisms and Osteonecrosis

Bone hypoxia resulting from impaired blood flow is the final pathway for the development of osteonecrosis (ON). The aim of this study was to evaluate if HIF-1α, the major transcription factor triggered by hypoxia, is genetically implicated in susceptibility to ON. For this we analyzed frequencies of...

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Detalles Bibliográficos
Autores principales: Chachami, Georgia, Kalousi, Alkmini, Papatheodorou, Loukia, Lyberopoulou, Aggeliki, Nasikas, Vasileios, Tanimoto, Keiji, Simos, George, Malizos, Konstantinos N., Georgatsou, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832621/
https://www.ncbi.nlm.nih.gov/pubmed/24260273
http://dx.doi.org/10.1371/journal.pone.0079647