Inhibition of GSK-3β Rescues the Impairments in Bone Formation and Mechanical Properties Associated with Fracture Healing in Osteoblast Selective Connexin 43 Deficient Mice

Connexin 43 (Cx43) is the most abundant gap junction protein in bone and is required for osteoblastic differentiation and bone homeostasis. During fracture healing, Cx43 is abundantly expressed in osteoblasts and osteocytes, while Cx43 deficiency impairs bone formation and healing. In the present st...

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Detalles Bibliográficos
Autores principales: Loiselle, Alayna E., Lloyd, Shane A. J., Paul, Emmanuel M., Lewis, Gregory S., Donahue, Henry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832658/
https://www.ncbi.nlm.nih.gov/pubmed/24260576
http://dx.doi.org/10.1371/journal.pone.0081399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832658/
https://www.ncbi.nlm.nih.gov/pubmed/24260576
http://dx.doi.org/10.1371/journal.pone.0081399

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