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Influence of Neuropathology on Convection-Enhanced Delivery in the Rat Hippocampus

Local drug delivery techniques, such as convention-enhanced delivery (CED), are promising novel strategies for delivering therapeutic agents otherwise limited by systemic toxicity and blood-brain-barrier restrictions. CED uses positive pressure to deliver infusate homogeneously into interstitial spa...

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Detalles Bibliográficos
Autores principales: Kantorovich, Svetlana, Astary, Garrett W., King, Michael A., Mareci, Thomas H., Sarntinoranont, Malisa, Carney, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832660/
https://www.ncbi.nlm.nih.gov/pubmed/24260433
http://dx.doi.org/10.1371/journal.pone.0080606