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C. elegans Aging Is Modulated by Hydrogen Sulfide and the sulfhydrylase/cysteine Synthase cysl-2
Exogenous hydrogen sulfide (H(2)S) administration and endogenous H(2)S metabolism were explored in the nematode C. elegans. Chronic treatment with a slow-releasing H(2)S donor, GYY4137, extended median survival by 17-23% and increased tolerance towards oxidative and endoplasmic reticulum (ER) stress...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832670/ https://www.ncbi.nlm.nih.gov/pubmed/24260346 http://dx.doi.org/10.1371/journal.pone.0080135 |