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C. elegans Aging Is Modulated by Hydrogen Sulfide and the sulfhydrylase/cysteine Synthase cysl-2
Exogenous hydrogen sulfide (H(2)S) administration and endogenous H(2)S metabolism were explored in the nematode C. elegans. Chronic treatment with a slow-releasing H(2)S donor, GYY4137, extended median survival by 17-23% and increased tolerance towards oxidative and endoplasmic reticulum (ER) stress...
Autores principales: | Qabazard, Bedoor, Ahmed, Samanza, Li, Ling, Arlt, Volker M., Moore, Philip K., Stürzenbaum, Stephen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832670/ https://www.ncbi.nlm.nih.gov/pubmed/24260346 http://dx.doi.org/10.1371/journal.pone.0080135 |
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