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Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion

While there have been numerous advances in our understanding of how apicomplexan parasites such as Toxoplasma gondii enter host cells, many of the signaling pathways and enzymes involved in the organization of invasion mediators remain poorly defined. We recently performed a forward chemical genetic...

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Detalles Bibliográficos
Autores principales: Child, Matthew A., Hall, Carolyn I., Beck, Josh R., Ofori, Leslie O., Albrow, Victoria E., Garland, Megan, Bowyer, Paul W., Bradley, Peter J., Powers, James C., Boothroyd, John C., Weerapana, Eranthie, Bogyo, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832678/
https://www.ncbi.nlm.nih.gov/pubmed/23934245
http://dx.doi.org/10.1038/nchembio.1315