Cargando…
Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion
While there have been numerous advances in our understanding of how apicomplexan parasites such as Toxoplasma gondii enter host cells, many of the signaling pathways and enzymes involved in the organization of invasion mediators remain poorly defined. We recently performed a forward chemical genetic...
Autores principales: | Child, Matthew A., Hall, Carolyn I., Beck, Josh R., Ofori, Leslie O., Albrow, Victoria E., Garland, Megan, Bowyer, Paul W., Bradley, Peter J., Powers, James C., Boothroyd, John C., Weerapana, Eranthie, Bogyo, Matthew |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832678/ https://www.ncbi.nlm.nih.gov/pubmed/23934245 http://dx.doi.org/10.1038/nchembio.1315 |
Ejemplares similares
-
Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1
por: Child, Matthew A., et al.
Publicado: (2017) -
Proteomic Analysis of Fractionated Toxoplasma Oocysts Reveals Clues to Their Environmental Resistance
por: Fritz, Heather M., et al.
Publicado: (2012) -
Identification of a S. aureus virulence factor by
activity-based protein profiling (ABPP)
por: Lentz, Christian S., et al.
Publicado: (2018) -
Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function
por: Engelberg, Klemens, et al.
Publicado: (2022) -
Michael addition-based probes for ratiometric fluorescence imaging of protein S-depalmitoylases in live cells and tissues
por: Beck, Michael W., et al.
Publicado: (2017)