The effect of hepatic or renal impairment on the pharmacokinetics of edivoxetine, a selective norepinephrine transporter reuptake inhibitor

PURPOSE: To assess the impact of hepatic or renal impairment on the pharmacokinetics (PK) of edivoxetine. METHODS: Two separate multi-center, open-label studies with males and females were conducted. Subjects were categorized according to their hepatic function, determined by the Child–Pugh classifi...

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Detalles Bibliográficos
Autores principales: Kielbasa, William, Tesfaye, Eshetu, Luffer-Atlas, Debra, Mitchell, Malcolm I., Turik, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832778/
https://www.ncbi.nlm.nih.gov/pubmed/23955175
http://dx.doi.org/10.1007/s00228-013-1572-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832778/
https://www.ncbi.nlm.nih.gov/pubmed/23955175
http://dx.doi.org/10.1007/s00228-013-1572-y

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