Plxnd1 Expression in Thymocytes Regulates Their Intrathymic Migration While That in Thymic Endothelium Impacts Medullary Topology

An important role for plexinD1 in thymic development is inferred from studies of germline Plxnd1 knockout (KO) mice where mislocalized CD69(+) thymocytes as well as ectopic thymic subcapsular medullary structures were observed. Given embryonic lethality of the Plxnd1(−/−) genotype, fetal liver trans...

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Detalles Bibliográficos
Autores principales: Choi, Young I., Duke-Cohan, Jonathan S., Tan, Jing, Gui, Jingang, Singh, Manvendra K., Epstein, Jonathan A., Reinherz, Ellis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832804/
https://www.ncbi.nlm.nih.gov/pubmed/24312099
http://dx.doi.org/10.3389/fimmu.2013.00392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832804/
https://www.ncbi.nlm.nih.gov/pubmed/24312099
http://dx.doi.org/10.3389/fimmu.2013.00392

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