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Evaluation of p21 promoter for interleukin 12 radiation induced transcriptional targeting in a mouse tumor model
BACKGROUND: Radiation induced transcriptional targeting is a gene therapy approach that takes advantage of the targeting abilities of radiotherapy by using radio inducible promoters to spatially and temporally limit the transgene expression. Cyclin dependent kinase inhibitor 1 (CDKN1A), also known a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832904/ https://www.ncbi.nlm.nih.gov/pubmed/24219565 http://dx.doi.org/10.1186/1476-4598-12-136 |