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Evaluation of p21 promoter for interleukin 12 radiation induced transcriptional targeting in a mouse tumor model

BACKGROUND: Radiation induced transcriptional targeting is a gene therapy approach that takes advantage of the targeting abilities of radiotherapy by using radio inducible promoters to spatially and temporally limit the transgene expression. Cyclin dependent kinase inhibitor 1 (CDKN1A), also known a...

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Detalles Bibliográficos
Autores principales: Kamensek, Urska, Sersa, Gregor, Cemazar, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832904/
https://www.ncbi.nlm.nih.gov/pubmed/24219565
http://dx.doi.org/10.1186/1476-4598-12-136

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