SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells

Prnp(−/−) mice lack the prion protein PrP(C) and are resistant to prion infections, but variable phenotypes have been reported in Prnp(−/−) mice and the physiological function of PrP(C) remains poorly understood. Here we examined a cell-autonomous phenotype, inhibition of macrophage phagocytosis of...

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Detalles Bibliográficos
Autores principales: Nuvolone, Mario, Kana, Veronika, Hutter, Gregor, Sakata, Daiji, Mortin-Toth, Steven M., Russo, Giancarlo, Danska, Jayne S., Aguzzi, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832919/
https://www.ncbi.nlm.nih.gov/pubmed/24145514
http://dx.doi.org/10.1084/jem.20131274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832919/
https://www.ncbi.nlm.nih.gov/pubmed/24145514
http://dx.doi.org/10.1084/jem.20131274

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