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SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells

Prnp(−/−) mice lack the prion protein PrP(C) and are resistant to prion infections, but variable phenotypes have been reported in Prnp(−/−) mice and the physiological function of PrP(C) remains poorly understood. Here we examined a cell-autonomous phenotype, inhibition of macrophage phagocytosis of...

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Detalles Bibliográficos
Autores principales:	Nuvolone, Mario, Kana, Veronika, Hutter, Gregor, Sakata, Daiji, Mortin-Toth, Steven M., Russo, Giancarlo, Danska, Jayne S., Aguzzi, Adriano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832919/ https://www.ncbi.nlm.nih.gov/pubmed/24145514 http://dx.doi.org/10.1084/jem.20131274

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