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CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells

HIV-1–infected macrophages likely represent viral reservoirs, as they accumulate newly formed virions in internal virus-containing compartments (VCCs). However, the nature and biogenesis of VCCs remain poorly defined. We show that upon HIV-1 infection of primary human macrophages, Gag is recruited t...

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Detalles Bibliográficos
Autores principales: Berre, Stefano, Gaudin, Raphaël, Cunha de Alencar, Bruna, Desdouits, Marion, Chabaud, Mélanie, Naffakh, Nadia, Rabaza-Gairi, Marc, Gobert, François-Xavier, Jouve, Mabel, Benaroch, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832921/
https://www.ncbi.nlm.nih.gov/pubmed/24145510
http://dx.doi.org/10.1084/jem.20130566