Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration

Excessive glutamate signaling is thought to underlie neurodegeneration in multiple contexts, yet the pro-degenerative signaling pathways downstream of glutamate receptor activation are not well defined. We show that dual leucine zipper kinase (DLK) is essential for excitotoxicity-induced degeneratio...

Descripción completa

Detalles Bibliográficos
Autores principales: Pozniak, Christine D., Sengupta Ghosh, Arundhati, Gogineni, Alvin, Hanson, Jesse E., Lee, Seung-Hye, Larson, Jessica L., Solanoy, Hilda, Bustos, Daisy, Li, Hong, Ngu, Hai, Jubb, Adrian M., Ayalon, Gai, Wu, Jiansheng, Scearce-Levie, Kimberly, Zhou, Qiang, Weimer, Robby M., Kirkpatrick, Donald S., Lewcock, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832926/
https://www.ncbi.nlm.nih.gov/pubmed/24166713
http://dx.doi.org/10.1084/jem.20122832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832926/
https://www.ncbi.nlm.nih.gov/pubmed/24166713
http://dx.doi.org/10.1084/jem.20122832

Ejemplares similares