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Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration

Excessive glutamate signaling is thought to underlie neurodegeneration in multiple contexts, yet the pro-degenerative signaling pathways downstream of glutamate receptor activation are not well defined. We show that dual leucine zipper kinase (DLK) is essential for excitotoxicity-induced degeneratio...

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Detalles Bibliográficos
Autores principales:	Pozniak, Christine D., Sengupta Ghosh, Arundhati, Gogineni, Alvin, Hanson, Jesse E., Lee, Seung-Hye, Larson, Jessica L., Solanoy, Hilda, Bustos, Daisy, Li, Hong, Ngu, Hai, Jubb, Adrian M., Ayalon, Gai, Wu, Jiansheng, Scearce-Levie, Kimberly, Zhou, Qiang, Weimer, Robby M., Kirkpatrick, Donald S., Lewcock, Joseph W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832926/ https://www.ncbi.nlm.nih.gov/pubmed/24166713 http://dx.doi.org/10.1084/jem.20122832

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