Annular PIP(3) accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse

The immunological synapse formed by a T lymphocyte on the surface of a target cell contains a peripheral ring of filamentous actin (F-actin) that promotes adhesion and facilitates the directional secretion of cytokines and cytolytic factors. We show that growth and maintenance of this F-actin ring i...

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Detalles Bibliográficos
Autores principales: Le Floc’h, Audrey, Tanaka, Yoshihiko, Bantilan, Niels S., Voisinne, Guillaume, Altan-Bonnet, Grégoire, Fukui, Yoshinori, Huse, Morgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832928/
https://www.ncbi.nlm.nih.gov/pubmed/24190432
http://dx.doi.org/10.1084/jem.20131324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832928/
https://www.ncbi.nlm.nih.gov/pubmed/24190432
http://dx.doi.org/10.1084/jem.20131324

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