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Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation

Human Langerhans cell (LC) precursors populate the epidermis early during prenatal development and thereafter undergo massive proliferation. The prototypic antiproliferative cytokine TGF-β1 is required for LC differentiation from human CD34(+) hematopoietic progenitor cells and blood monocytes in vi...

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Detalles Bibliográficos
Autores principales: Yasmin, Nighat, Bauer, Thomas, Modak, Madhura, Wagner, Karin, Schuster, Christopher, Köffel, Rene, Seyerl, Maria, Stöckl, Johannes, Elbe-Bürger, Adelheid, Graf, Daniel, Strobl, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832935/
https://www.ncbi.nlm.nih.gov/pubmed/24190429
http://dx.doi.org/10.1084/jem.20130275