Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders

Polycomb group (PcG) proteins are essential regulators of hematopoietic stem cells. Recent extensive mutation analyses of the myeloid malignancies have revealed that inactivating somatic mutations in PcG genes such as EZH2 and ASXL1 occur frequently in patients with myelodysplastic disorders includi...

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Detalles Bibliográficos
Autores principales: Muto, Tomoya, Sashida, Goro, Oshima, Motohiko, Wendt, George R., Mochizuki-Kashio, Makiko, Nagata, Yasunobu, Sanada, Masashi, Miyagi, Satoru, Saraya, Atsunori, Kamio, Asuka, Nagae, Genta, Nakaseko, Chiaki, Yokote, Koutaro, Shimoda, Kazuya, Koseki, Haruhiko, Suzuki, Yutaka, Sugano, Sumio, Aburatani, Hiroyuki, Ogawa, Seishi, Iwama, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832936/
https://www.ncbi.nlm.nih.gov/pubmed/24218139
http://dx.doi.org/10.1084/jem.20131144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832936/
https://www.ncbi.nlm.nih.gov/pubmed/24218139
http://dx.doi.org/10.1084/jem.20131144

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