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Transcriptional Regulation of Δ6-Desaturase by Peroxisome Proliferative-Activated Receptor δ Agonist in Human Pancreatic Cancer Cells: Role of MEK/ERK1/2 Pathway

The Δ6-desaturase (Δ6D), also known as fatty acid desaturase 2, is a regulatory enzyme in de novo fatty acid synthesis, which has been linked to obesity and diabetes. The aim of the present study was to investigate the effect of peroxisome proliferative-activated receptor δ (PPARδ) agonist and MEK/E...

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Detalles Bibliográficos
Autores principales: Darabi, Maryam, Byagowi, Shima, Fayezi, Shabnam, Darabi, Masoud, Mirshahvaladi, Shahab, Sahmani, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832962/
https://www.ncbi.nlm.nih.gov/pubmed/24294133
http://dx.doi.org/10.1155/2013/607524