DICER1 hotspot mutations in non-epithelial gonadal tumours

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BACKGROUND: Non-epithelial gonadal tumours largely comprise sex cord-stromal tumours (SCSTs) and germ cell tumours (GCTs). Specific somatic mutations in DICER1, a microRNA maturation pathway gene, have been identified in these tumours. We conducted a study that aimed to confirm, refine and extend th...

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Detalles Bibliográficos
Autores principales: Witkowski, L, Mattina, J, Schönberger, S, Murray, M J, Huntsman, D G, Reis-Filho, J S, McCluggage, W G, Nicholson, J C, Coleman, N, Calaminus, G, Schneider, D T, Arseneau, J, Stewart, C J R, Foulkes, W D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833222/
https://www.ncbi.nlm.nih.gov/pubmed/24136150
http://dx.doi.org/10.1038/bjc.2013.637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833222/
https://www.ncbi.nlm.nih.gov/pubmed/24136150
http://dx.doi.org/10.1038/bjc.2013.637

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