A c-Met inhibitor increases the chemosensitivity of cancer stem cells to the irinotecan in gastric carcinoma

BACKGROUND: Cancer stem cells (CSCs) may be postulated mediators of the chemoresistance. This study aimed to determine an effective signal inhibitor with effects on the proliferation of CSCs in combination with anticancer drugs. METHODS: We used three gastric cancer cell lines and three side populat...

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Detalles Bibliográficos
Autores principales: Yashiro, M, Nishii, T, Hasegawa, T, Matsuzaki, T, Morisaki, T, Fukuoka, T, Hirakawa, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833223/
https://www.ncbi.nlm.nih.gov/pubmed/24129235
http://dx.doi.org/10.1038/bjc.2013.638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833223/
https://www.ncbi.nlm.nih.gov/pubmed/24129235
http://dx.doi.org/10.1038/bjc.2013.638

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