ALK gene amplification is associated with poor prognosis in colorectal carcinoma

BACKGROUND: Recently, the anaplastic lymphoma kinase (ALK) has been found to be altered in several solid and haematological tumours. ALK gene copy number changes and mutations in colorectal cancers (CRCs) are not well characterised. We aimed to study the prevalence of ALK copy number changes, transl...

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Detalles Bibliográficos
Autores principales: Bavi, P, Jehan, Z, Bu, R, Prabhakaran, S, Al-Sanea, N, Al-Dayel, F, Al-Assiri, M, Al-Halouly, T, Sairafi, R, Uddin, S, Al-Kuraya, K S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833224/
https://www.ncbi.nlm.nih.gov/pubmed/24129244
http://dx.doi.org/10.1038/bjc.2013.641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833224/
https://www.ncbi.nlm.nih.gov/pubmed/24129244
http://dx.doi.org/10.1038/bjc.2013.641

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