Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells

BACKGROUND: Breast cancer stem cells (BCSCs) are characterized by high aldehyde dehydrogenase (ALDH) enzyme activity and are refractory to current treatment modalities, show a higher risk for metastasis, and influence the epithelial to mesenchymal transition (EMT), leading to a shorter time to recur...

Descripción completa

Detalles Bibliográficos
Autores principales: Suman, S, Das, T P, Damodaran, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833225/
https://www.ncbi.nlm.nih.gov/pubmed/24129237
http://dx.doi.org/10.1038/bjc.2013.642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833225/
https://www.ncbi.nlm.nih.gov/pubmed/24129237
http://dx.doi.org/10.1038/bjc.2013.642

Ejemplares similares