Deciphering the pathogenesis of sporadic Creutzfeldt-Jakob disease with codon 129 M/V and type 2 abnormal prion protein

BACKGROUND: Sporadic Creutzfeldt-Jakob disease is classified according to the genotype at polymorphic codon 129 (M or V) of the prion protein (PrP) gene and the type (1 or 2) of abnormal isoform of PrP (PrP(Sc)) in the brain. The most complicated entity in the current classification system is MV2, s...

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Detalles Bibliográficos
Autores principales: Kobayashi, Atsushi, Iwasaki, Yasushi, Otsuka, Hiroyuki, Yamada, Masahito, Yoshida, Mari, Matsuura, Yuichi, Mohri, Shirou, Kitamoto, Tetsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833290/
https://www.ncbi.nlm.nih.gov/pubmed/24252157
http://dx.doi.org/10.1186/2051-5960-1-74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833290/
https://www.ncbi.nlm.nih.gov/pubmed/24252157
http://dx.doi.org/10.1186/2051-5960-1-74

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