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PI3-kinase inhibition synergistically promoted the anti-tumor effect of lupeol in hepatocellular carcinoma

BACKGROUND: Lup-20(29)-en-3H-ol (Lupeol), a dietary triterpene, has been shown to possess multiple pharmacological activities including anti-tumor effects METHODS: In the current study, we noted that low doses of lupeol (<40 μM) promoted the growth of hepatocellular carcinoma (HCC) cells with a s...

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Detalles Bibliográficos
Autores principales: Liu, Fen, He, Yan, Liang, Yong, Wen, Lijun, Zhu, Yongming, Wu, Yan, Zhao, Lixiang, Li, Yunsen, Mao, Xinliang, Liu, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833314/
https://www.ncbi.nlm.nih.gov/pubmed/24176221
http://dx.doi.org/10.1186/1475-2867-13-108