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Aging increases the oxidation of dichlorohydrofluorescein in single isolated skeletal muscle fibers at rest, but not during contractions

An increase in the activity of reactive oxygen species (ROS) has been implicated in the mechanisms of loss of skeletal muscle that occurs during aging, but few studies have attempted to directly assess activities in intact muscle fibers. The current project used the nonspecific fluorescent probe for...

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Detalles Bibliográficos
Autores principales: Palomero, Jesus, Vasilaki, Aphrodite, Pye, Deborah, McArdle, Anne, Jackson, Malcolm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833391/
https://www.ncbi.nlm.nih.gov/pubmed/23697797
http://dx.doi.org/10.1152/ajpregu.00530.2012