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microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart

microRNA-1 (miR-1) is an evolutionarily conserved, striated muscle-enriched miRNA. Most mammalian genomes contain two copies of miR-1, and in mice, deletion of a single locus, miR-1-2, causes incompletely penetrant lethality and subtle cardiac defects. Here, we report that deletion of miR-1-1 result...

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Detalles Bibliográficos
Autores principales:	Heidersbach, Amy, Saxby, Chris, Carver-Moore, Karen, Huang, Yu, Ang, Yen-Sin, de Jong, Pieter J, Ivey, Kathryn N, Srivastava, Deepak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2013
Materias:	Developmental Biology and Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833424/ https://www.ncbi.nlm.nih.gov/pubmed/24252873 http://dx.doi.org/10.7554/eLife.01323

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