Accelerated homologous recombination and subsequent genome modification in Drosophila

Gene targeting by ‘ends-out’ homologous recombination enables the deletion of genomic sequences and concurrent introduction of exogenous DNA with base-pair precision without sequence constraint. In Drosophila, this powerful technique has remained laborious and hence seldom implemented. We describe a...

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Detalles Bibliográficos
Autores principales: Baena-Lopez, Luis Alberto, Alexandre, Cyrille, Mitchell, Alice, Pasakarnis, Laurynas, Vincent, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2013
Materias:
Techniques and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833436/
https://www.ncbi.nlm.nih.gov/pubmed/24154526
http://dx.doi.org/10.1242/dev.100933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833436/
https://www.ncbi.nlm.nih.gov/pubmed/24154526
http://dx.doi.org/10.1242/dev.100933

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