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Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF-7 breast cancer cells

Apoptosis is controlled by the BCL-2 family of proteins, which can be divided into three different subclasses based on the conservation of BCL-2 homology domains. BIK is a founding member of the BH3-only pro-apoptotic protein family. BIK is predominantly localized in the endoplasmic reticulum (ER) a...

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Detalles Bibliográficos
Autores principales: VIEDMA-RODRIGUEZ, RUBÍ, BAIZA-GUTMAN, LUIS ARTURO, GARCÍA-CARRANCÁ, ALEJANDRO, MORENO-FIERROS, LETICIA, SALAMANCA-GÓMEZ, FABIO, ARENAS-ARANDA, DIEGO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833859/
https://www.ncbi.nlm.nih.gov/pubmed/24100375
http://dx.doi.org/10.3892/ijo.2013.2127