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Simvastatin reduces melanoma progression in a murine model

Statins are a class of drugs that inhibit the rate-limiting step in the cholesterol biosynthetic pathway and show an anticancer effect, probably through the inhibition of cell proliferation. To date, the exact mechanism of cancer cell growth arrest induced by statins is not known. We report that sim...

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Detalles Bibliográficos
Autores principales: ZANFARDINO, MARIO, SPAMPANATO, CARMINE, DE CICCO, ROSANNA, BUOMMINO, ELISABETTA, DE FILIPPIS, ANNA, BAIANO, SALVATORE, BARRA, ADRIANO, MORELLI, FRANCO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833984/
https://www.ncbi.nlm.nih.gov/pubmed/24101161
http://dx.doi.org/10.3892/ijo.2013.2126