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Estrogen Receptor and PI3K/Akt Signaling Pathway Involvement in S-(-)Equol-Induced Activation of Nrf2/ARE in Endothelial Cells

S-(-)equol, a natural product of the isoflavone daidzein, has been reported to offer cytoprotective effects with respect to the cardiovascular system, but how this occurs is unclear. Interestingly, S-(-)equol is produced by the human gut, suggesting a role in physiological processes. We report that...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Liang, Xinyu, Shi, Linying, Wang, Li, Chen, Junli, Kang, Chao, Zhu, Jundong, Mi, Mantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833998/
https://www.ncbi.nlm.nih.gov/pubmed/24260155
http://dx.doi.org/10.1371/journal.pone.0079075