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TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis
Severe sepsis is often accompanied by acute kidney injury (AKI) and albuminuria. Here we studied whether the AKI and albuminuria associated with lipopolysaccharide (LPS) treatment in mice reflects impairment of the glomerular endothelium with its associated endothelial surface layer. LPS treatment d...
Autores principales: | Xu, Chang, Chang, Anthony, Hack, Bradley K., Eadon, Michael T., Alper, Seth L., Cunningham, Patrick N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834073/ https://www.ncbi.nlm.nih.gov/pubmed/23903370 http://dx.doi.org/10.1038/ki.2013.286 |
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