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Transcriptomic Analysis Reveals Novel Mechanistic Insight into Murine Biological Responses to Multi-Walled Carbon Nanotubes in Lungs and Cultured Lung Epithelial Cells

There is great interest in substituting animal work with in vitro experimentation in human health risk assessment; however, there are only few comparisons of in vitro and in vivo biological responses to engineered nanomaterials. We used high-content genomics tools to compare in vivo pulmonary respon...

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Detalles Bibliográficos
Autores principales: Søs Poulsen, Sarah, Jacobsen, Nicklas R., Labib, Sarah, Wu, Dongmei, Husain, Mainul, Williams, Andrew, Bøgelund, Jesper P., Andersen, Ole, Købler, Carsten, Mølhave, Kristian, Kyjovska, Zdenka O., Saber, Anne T., Wallin, Håkan, Yauk, Carole L., Vogel, Ulla, Halappanavar, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834097/
https://www.ncbi.nlm.nih.gov/pubmed/24260392
http://dx.doi.org/10.1371/journal.pone.0080452