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Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma

BACKGROUND: An imbalance between proliferation and apoptosis is one of the main features of carcinogenesis. TRAIL (TNF-related apoptosis-inducing ligand) induces apoptosis upon binding to the TRAIL death receptors, TRAIL receptor 1 (TRAIL-R1) and TRAIL-R2, whereas binding to TRAIL-R3 and TRAIL-R4 mi...

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Detalles Bibliográficos
Autores principales: Koschny, Ronald, Brost, Sylvia, Hinz, Ulf, Sykora, Jaromir, Batke, Emanuela M, Singer, Stephan, Breuhahn, Kai, Stremmel, Wolfgang, Walczak, Henning, Schemmer, Peter, Schirmacher, Peter, Ganten, Tom M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834100/
https://www.ncbi.nlm.nih.gov/pubmed/24209510
http://dx.doi.org/10.1186/1471-2407-13-532