Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

BACKGROUND: Atopic dermatitis (AD) is a major inflammatory condition of the skin caused by inherited skin barrier deficiency, with mutations in the filaggrin gene predisposing to development of AD. Support for barrier deficiency initiating AD came from flaky tail mice, which have a frameshift mutati...

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Detalles Bibliográficos
Autores principales: Saunders, Sean P., Goh, Christabelle S.M., Brown, Sara J., Palmer, Colin N.A., Porter, Rebecca M., Cole, Christian, Campbell, Linda E., Gierlinski, Marek, Barton, Geoffrey J., Schneider, Georg, Balmain, Allan, Prescott, Alan R., Weidinger, Stephan, Baurecht, Hansjörg, Kabesch, Michael, Gieger, Christian, Lee, Young-Ae, Tavendale, Roger, Mukhopadhyay, Somnath, Turner, Stephen W., Madhok, Vishnu B., Sullivan, Frank M., Relton, Caroline, Burn, John, Meggitt, Simon, Smith, Catherine H., Allen, Michael A., Barker, Jonathan N.W. N., Reynolds, Nick J., Cordell, Heather J., Irvine, Alan D., McLean, W.H. Irwin, Sandilands, Aileen, Fallon, Padraic G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby 2013
Materias:
Atopic Dermatitis and Skin Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834151/
https://www.ncbi.nlm.nih.gov/pubmed/24084074
http://dx.doi.org/10.1016/j.jaci.2013.08.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834151/
https://www.ncbi.nlm.nih.gov/pubmed/24084074
http://dx.doi.org/10.1016/j.jaci.2013.08.046

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