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RedOx Status, Proteasome and APEH: Insights into Anticancer Mechanisms of t10,c12-Conjugated Linoleic Acid Isomer on A375 Melanoma Cells

This study describes the investigation of the efficiency of conjugated linoleic acid (CLA) isomers in reducing cancer cells viability exploring the role of the oxidative stress and acylpeptide hydrolase (APEH)/proteasome mediated pathways on pro-apoptotic activity of the isomer trans10,cis12 (t10,c1...

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Detalles Bibliográficos
Autores principales: Bergamo, Paolo, Cocca, Ennio, Palumbo, Rosanna, Gogliettino, Marta, Rossi, Mose, Palmieri, Gianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834215/
https://www.ncbi.nlm.nih.gov/pubmed/24260504
http://dx.doi.org/10.1371/journal.pone.0080900