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Chromogranin A and Its Fragments as Regulators of Small Intestinal Neuroendocrine Neoplasm Proliferation

INTRODUCTION: Chromogranin A is a neuroendocrine secretory product and its loss is a feature of malignant NEN de-differentiation. We hypothesized that chromogranin A fragments were differentially expressed during NEN metastasis and played a role in the regulation of NEN proliferation. METHODS: Chrom...

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Detalles Bibliográficos
Autores principales: Giovinazzo, Francesco, Schimmack, Simon, Svejda, Bernhard, Alaimo, Daniele, Pfragner, Roswitha, Modlin, Irvin, Kidd, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834250/
https://www.ncbi.nlm.nih.gov/pubmed/24260544
http://dx.doi.org/10.1371/journal.pone.0081111