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Development of NMDAR Antagonists with Reduced Neurotoxic Side Effects: a Study on GK11

The NMDAR glutamate receptor subtype mediates various vital physiological neuronal functions. However, its excessive activation contributes to neuronal damage in a large variety of acute and chronic neurological disorders. NMDAR antagonists thus represent promising therapeutic tools that can counter...

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Detalles Bibliográficos
Autores principales: Vandame, Delphine, Ulmann, Lauriane, Teigell, Marisa, Prieto-Cappellini, Monica, Vignon, Jacques, Privat, Alain, Perez-Polo, Regino, Nesic, Olivera, Hirbec, Helene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834252/
https://www.ncbi.nlm.nih.gov/pubmed/24260528
http://dx.doi.org/10.1371/journal.pone.0081004