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Development of NMDAR Antagonists with Reduced Neurotoxic Side Effects: a Study on GK11
The NMDAR glutamate receptor subtype mediates various vital physiological neuronal functions. However, its excessive activation contributes to neuronal damage in a large variety of acute and chronic neurological disorders. NMDAR antagonists thus represent promising therapeutic tools that can counter...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834252/ https://www.ncbi.nlm.nih.gov/pubmed/24260528 http://dx.doi.org/10.1371/journal.pone.0081004 |