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P53 regulates the migration of mesenchymal stromal cells in response to the tumor microenvironment through both CXCL12-dependent and -independent mechanisms

Mesenchymal stromal cells (MSCs) are multipotent fibroblast-like cells located in the bone marrow that localize to areas of tissue damage including wounds and solid tumors. Within the tumor microenvironment, MSCs adopt the phenotype of carcinoma-associated fibroblasts (CAFs) and stimulate tumor grow...

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Detalles Bibliográficos
Autores principales: LIN, SIANG-YO, DOLFI, SONIA C., AMIRI, SOHRAB, LI, JAIDONG, BUDAK-ALPDOGAN, TULIN, LEE, KUO-CHIEH, DERENZO, CHRISTOPHER, BANERJEE, DEBABRATA, GLOD, JOHN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834256/
https://www.ncbi.nlm.nih.gov/pubmed/24064862
http://dx.doi.org/10.3892/ijo.2013.2109