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Down-Regulating Overexpressed Human Lon in Cervical Cancer Suppresses Cell Proliferation and Bioenergetics

The human mitochondrial ATP-dependent Lon protease functions in regulating the metabolism and quality control of proteins and mitochondrial DNA (mtDNA). However, the role of Lon in cancer is not well understood. Therefore, this study was undertaken to investigate the importance of Lon in cervical ca...

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Detalles Bibliográficos
Autores principales: Nie, Xiaobo, Li, Min, Lu, Bin, Zhang, Yuxin, Lan, Linhua, Chen, Lin, Lu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834287/
https://www.ncbi.nlm.nih.gov/pubmed/24260536
http://dx.doi.org/10.1371/journal.pone.0081084