Cargando…
Down-Regulating Overexpressed Human Lon in Cervical Cancer Suppresses Cell Proliferation and Bioenergetics
The human mitochondrial ATP-dependent Lon protease functions in regulating the metabolism and quality control of proteins and mitochondrial DNA (mtDNA). However, the role of Lon in cancer is not well understood. Therefore, this study was undertaken to investigate the importance of Lon in cervical ca...
Autores principales: | Nie, Xiaobo, Li, Min, Lu, Bin, Zhang, Yuxin, Lan, Linhua, Chen, Lin, Lu, Jianxin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834287/ https://www.ncbi.nlm.nih.gov/pubmed/24260536 http://dx.doi.org/10.1371/journal.pone.0081084 |
Ejemplares similares
-
Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer
por: Liu, Yongzhang, et al.
Publicado: (2014) -
Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer
por: Quirós, Pedro M, et al.
Publicado: (2014) -
LonP1 Links Mitochondria–ER Interaction to Regulate Heart Function
por: Li, Yujie, et al.
Publicado: (2023) -
Oxidative stress regulates cellular bioenergetics in esophageal squamous cell carcinoma cell
por: Zhang, Xiaolong, et al.
Publicado: (2017) -
The LonDownS adult cognitive assessment to study cognitive abilities and decline in Down syndrome
por: Startin, Carla M., et al.
Publicado: (2016)